The two-domain elevator-type mechanism of zinc-transporting zip proteins

HIGHLIGHTS

• who: STRUCTURAL BIOLOGY et al. from the wnloaded from https://wwwscience.org at Umea University on August, have published the research work: The two-domain elevator-type mechanism of zinc-transporting ZIP proteins, in the Journal: (JOURNAL) of 13/07/2022
• what: The analysis reveals a considerable displacement of the transport domain, with the ion-free form being shifted around 3 Å toward the intracellular inside, combined with a substantial twist that tilts the domain 11°. The authors propose that ZIPs form scaffold domain-based dimers and exploit an oscillating elevator-type mechanism. The authors unraveled . . .
  

   

  

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