The tyrosine phosphatase shp2: a new target for insulin resistance?

HIGHLIGHTS

  • who: Cu00e9line Saint-Laurent et al. from the Ecole Nationale Vu00e9tu00e9rinaire de Toulouse, Toulouse, France Toulouse University Hospital, Toulouse, France have published the research work: The Tyrosine Phosphatase SHP2: A New Target for Insulin Resistance?, in the Journal: Biomedicines 2022, 10, 2139. of /2022/
  • what: The advent of genetically engineered animal models, aiming at suppressing SHP2 expression or expressing hyperactive mutants in specific tissues or organs, allowed documenting the metabolic impact of its targeted dysfunction and further supported a protective role for SHP2 in insulin resistance.

SUMMARY

    This phenotype has been . . .

     

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