The ufm1 system regulates er-phagy through the ufmylation of cyb5r3

HIGHLIGHTS

  • who: Ryosuke Ishimura from the (UNIVERSITY) have published the research work: The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3, in the Journal: (JOURNAL) of 28/01/2022
  • what: The authors focused on NADH-cytochrome b5 reductase 3 (CYB5R3) since this protein was identified by both screenings and is known to be anchored on the ER and/or mitochondrial membranes by myristoylation of the N-terminal Gly and a membrane-bound domain24 (Fig 1c). The authors focused on neurological studies in the mutant mice. To ufmylation of the ribosomal protein RPL26, which is . . .

     

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