The underestimated role of the p53 pathway in renal cancer

HIGHLIGHTS

  • who: Alessandra Amendolare and colleagues from the Department of Biosciences, Biotechnologies and Environment, University of Bari Aldo Moro, Bari, Italy have published the Article: The Underestimated Role of the p53 Pathway in Renal Cancer, in the Journal: Cancers 2022, 5733 of /2022/
  • what: Among cancers showing a low rate of p53 mutations and poor response to conventional therapies, RCC represents an extraordinary example of the importance of p53 pathway alter- 11 of 15 ations in therapy resistance.
  • future: P53 and its isoforms are key factors in mediating cell response and cell sensitivity to . . .

     

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