The unfolded protein response plays a predominant homeostatic role in response to mitochondrial stress in pancreatic stellate cells

HIGHLIGHTS

• who: Hsin-Yuan Su and collaborators from the Editor:, University of Valencia, SPAIN have published the research: The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0148999]. February 5, 2016 of /1371/
• what: Using primary and immortalized mouse PaSC the authors assess relative contributions of AMPK/mTOR signaling autophagy and UPR to cell fate responses during metabolic stress induced by mitochondrial dysfunction. mitochondrial uncoupler rottlerin at low doses (0.5-2.5 μM) was added to . . .
  

   

  

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