The unusual cosubstrate speci fi city of nqo2: conservation throughout the amniotes and implications for cellular function

HIGHLIGHTS

  • who: The Unusual Cosubstrate Specificity et al. from the Department of Biochemistry, University of Western Ontario, London, ON, Canada, Department of Pharmaceutical Chemistry have published the research: The Unusual Cosubstrate Speci fi city of NQO2: Conservation Throughout the Amniotes and Implications for Cellular Function, in the Journal: (JOURNAL)
  • how: This work yielded two NQO2-knockout HCT116 cell lines that have been used to probe the cellular function of NQO2.

SUMMARY

    NQO2 is actually able to use a variety of small reducing dihydronicotinamide cosubstrates efficiently, many of which are synthetic and not . . .

     

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