The us9-derived protein gptb9tm modulates app processing without targeting secretase activities

HIGHLIGHTS

  • who: Renato Brandimarti from the Department of Pharmacology and Physiology, Drexel University College of Medicine, , th Street, Philadelphia, PA, USA have published the paper: The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities, in the Journal: (JOURNAL)
  • what: This work has led the authors to envision US9 as a tool to alter APP processing toward the goal of neuroprotection. The authors report gPTB9TM`s ability to reduce APP Molecular Neurobiology 60:1811-1825 u03b2-cleavage in various cells and under different amyloidogenic stimuli. Plasmids generated in this study have been sequenced to . . .

     

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