The value of myocardium and kidney histopathological and immunohistochemical findings in accidental hypothermia-related fatalities

HIGHLIGHTS

SUMMARY

    Despite the progress made during recent decades in forensic pathology, the postmortem diagnosis of hypothermia is still a challenge. The nonspecific microscopic findings that are suggestive of hypothermia diagnosis include cardiac and neuronal hypoxic changes, pancreatic cell necrosis with leukocytes infiltration, along with the vacuolisation of cardiac myocytes, hepatocytes, and renal tubular epithelial_cells. In this respect, the study performed by Zhou et_al, in an experimental model, has shown that a significant metabolic disruption associated with lipid mobilisation from the tissue stores and their deposition in the cytoplasm of renal tubular cells is not specific . . .

     

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