HIGHLIGHTS
- who: CC Harris from the LaboratoryMD, USA have published the research work: The Walter Hubert Lecture -molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene, in the Journal: (JOURNAL)
- future: Study of the frequency timing and mutational spectra of p53 and other cancer-related genes provides insights into the aetiology and molecular pathogenesis of cancer and generates hypotheses for future investigations.
SUMMARY
The missense class of mutations can cause both a loss of tumoursuppressor function and a gain of oncogenic function by changing the . . .

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