Theaflavin-3,3 ′ -digallate inhibits erastin-induced chondrocytes ferroptosis via the nrf2/gpx4 signaling pathway in osteoarthritis

HIGHLIGHTS

  • who: Osteoarthritis and colleagues from the Truma Central, The Affiliated Changzhou No, People`s Hospital with Nanjing Medical University, Xinglong Alley, Changzhou, China have published the research work: Theaflavin-3,3 u2032 -Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis, in the Journal: Oxidative Medicine and Cellular Longevity of 17/Nov/2022
  • what: The study showed that TF3 elevates the expression of Slc7a11, suggesting that Slc7a11 mediates TF3 antiferroptosis effect.
  • how: The results showed that Gpx4 expression was markedly downregulated in the chondrocytes of OA patients. The . . .

     

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