Therapeutic and diagnostic implications of t cell scarring in celiac disease and beyond

HIGHLIGHTS

• who: Asbjørn Christophersen from the CentreUniversity of have published the paper: Therapeutic and Diagnostic Implications of T Cell Scarring in Celiac Disease and Beyond, in the Journal: (JOURNAL)
• what: This approach has been explored for pMHC-II complexes relevant to mouse models of T1D, MS and RA as well as for pMHC-I complexes relevant to mouse models of T1D . This study shows that in a human autoimmune disease it is possible to eliminate distinct T_cell clones based on their individual metabolic profiles.
• how: The same drug was tested for CeD (NCT00540657 . . .
  

   

  

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