Therapeutic effects of fc gamma riv inhibition are mediated by selectively blocking immune complex-induced neutrophil activation in epidermolysis bullosa acquisita

HIGHLIGHTS

  • who: Swantje C. Haeger from the Osaka City University, Japan have published the paper: Therapeutic effects of Fc gamma RIV inhibition are mediated by selectively blocking immune complex-induced neutrophil activation in epidermolysis bullosa acquisita, in the Journal: (JOURNAL)
  • what: The aim of this study was to explore the mechanistic role of FcgRIV in inducing autoantibody-induced tissue injury in EBA.
  • future: Mechanistic studies are required to validate this hypothesis.

SUMMARY

    In a previous study using the autoantibody transfer-induced murine model of EBA, mice lacking the common g . . .

     

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