HIGHLIGHTS
SUMMARY
In 2010, a large meta-analysis included 17,052 IBD patients and reported an overall risk of cancer "at any site" that was not significantly increased (SIR 1.10, 95% CI 0.96-1.27). A site-specific analysis demonstrated a higher risk of upper gastrointestinal tract, lung, urinary bladder, and skin cancers among Crohn`s disease (CD) patients, and liver-biliary cancer and leukemia in ulcerative colitis (UC) patients. Major evidence applies to the incident cancer risk on immunosuppressed patients and it demonstrates an increased risk of lymphoma and nonmelanoma skin cancer (NMSC . . .
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