Therapeutic potential of targeting periostin in the treatment of graves’ orbitopathy

HIGHLIGHTS

  • who: Sun Young Jang from the Department of Ophthalmology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of United States have published the research: Therapeutic Potential of Targeting Periostin in the Treatment of Gravesu2019 Orbitopathy, in the Journal: (JOURNAL)
  • what: This study was designed to investigate the role of periostin in the pathogenesis of GO. The authors demonstrate that IL-1b (10 ng/ml) remarkably enhanced production of periostin protein in a time-dependent manner in western blot analysis . The authors identified higher expression of POSTN gene in GO tissues compared to normal healthy orbital tissue . . .

     

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