HIGHLIGHTS
- who: Daniel Meraviglia-Crivelli and collaborators from the Molecular Therapeutics Program, Center for Applied Medical Research, CIMA, University of Navarra, Pamplona, Spain have published the Article: Therapeutic Strategies to Enhance Tumor Antigenicity: Making the Tumor Detectable by the Immune System, in the Journal: Biomedicines 2022, 10, 1842. of /2022/
- what: Preclinical data from this study showed that DAC might induce the demethylation of aberrant CpG islands producing dsRNAs that end up in the upregulation of type-III interferons (IFN).
- how: The concept was tested in different phase-I clinical trials in glioblastoma patients . . .
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