Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response

HIGHLIGHTS

• who: Dong-Rui Wang from the , [29, ]This discovery paved the way for Allison`s team to test whether blocking , can potentiate antitumor immunity and inhibit the growth of immunosuppressive tumors. At the end of, Allison`s team developed an antagonistic , antibody to be evaluated in tumor-bearing mice and later reported the ground-breaking discovery that blocking , can increase the antitumor activity of T cells and inhibit tumor growth [31]. Therefore, for the first time, it was demonstrated that inhibiting a negative immune regulator could suppress tumor progression have published the article: Therapeutic targets and biomarkers . . .
  

   

  

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