HIGHLIGHTS
- who: Commentary and colleagues from the Comenius University have published the research work: These authors contributed equally to this work. Received: 16 March 2021 Revised: 08 April 2021 Accepted: 12 April 2021 Version of Record published: 21 April, in the Journal: (JOURNAL) of 21/04/2021
- what: The study showed in_vivo that three weeks of captopril (ACEI) or candesartan (ARB) treatment up-regulates the ACE2 expression associated with increased ACE2 enzymatic activity in the lungs of young healthy rats.
- future: Some suggestions for future research are emerging Could the effects presented by Pedrosa . . .

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