Thioquinoline derivatives conjugated to thiosemicarbazide as potent tyrosinase inhibitors with anti-melanogenesis properties

HIGHLIGHTS

• who: Milad Noori from the Tehran University of Medical Sciences, Shiraz, Iran have published the research: Thioquinoline derivatives conjugated to thiosemicarbazide as potent tyrosinase inhibitors with anti-melanogenesis properties, in the Journal: Scientific Reports Scientific Reports
• what: Following our expertise in the rational design of tyrosinase inhibitors; herein, a series of thiosemicarbazidethioquinoline derivatives bearing different aryl-acetamides were designed and synthesized.
• how: The toxicity of all derivatives against HEK 293 as a normal cell line was evaluated by MTT assay and the results were presented in Table 9.

SUMMARY

 



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