Thiosulfate-cyanide sulfurtransferase a mitochondrial essential enzyme: from cell metabolism to the biotechnological applications

HIGHLIGHTS

  • who: Silvia Buonvino et al. from the Department of Chemical Sciences and Technology, University of Rome Tor Vergata, Via della Ricerca Scientifica , have published the research: Thiosulfate-Cyanide Sulfurtransferase a Mitochondrial Essential Enzyme: From Cell Metabolism to the Biotechnological Applications, in the Journal: (JOURNAL)

SUMMARY

    TST/rhodanese accepts a sulfane sulfur atom from a donor (e_g, thiosulfate), with the formation of a covalent enzyme-sulfur intermediate (E-S) characterized by a persulfide bond at the sulfhydryl group of the reactive cysteine in the active_site (Cys 247 in bovine TST); subsequently, the persulfide sulfur . . .

     

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