HIGHLIGHTS
- who: Mengbiao Guo and colleagues from the Huazhong Agricultural University have published the research: Three-dimensional and single-cell sequencing of liver cancer reveals comprehensive host-virus interactions in HBV infection, in the Journal: (JOURNAL)
- what: The work demonstrated that HBV can change the human genome organization globally, related to inflammatory responses, and potentially activated certain host genes and transposable_elements (TE, long genomic repeats) specifically to promote viral_replication. HBV integration is one of the main reasons that HBV infection is difficult to cure. The authors performed a comprehensive analysis of HBV impact on 3D genome . . .
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