HIGHLIGHTS
- who: Corinna Bingel from the Department University Hospital Ilmenau, Ilmenau, Germany have published the research: Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance, in the Journal: (JOURNAL)
- what: The authors show that 3D culture models are a suitable tool for screening drug responses of tumors. As the authors have previously shown the importance of the autophagic degradation pathway in neuroblastoma cell cultures, the authors focused on genes associated with the Gene Ontology (GO) term ‘autophagy' (GO:006914) and used the globaltest R package34 to check for differential regulation between 2D and . . .
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