Three distinct mechanisms underlying human γδ t cell-mediated cytotoxicity against malignant pleural mesothelioma

HIGHLIGHTS

• who: Yasuhiro Umeyama et al. from the Germany University of Oxford, United Kingdom have published the research work: Three distinct mechanisms underlying human u03b3u03b4 T cell-mediated cytotoxicity against malignant pleural mesothelioma, in the Journal: (JOURNAL)
• what: The authors first expanded gd T_cells derived from healthy donors with PTA/IL-2 and examined the effect of them on MPM cells in the absence or presence of antigens or monoclonal_antibodies.
• how: Since NKG2D DNAM-1 and CD16 are known to be expressed on natural killer (NK) cells the authors examined cytotoxic activity of the . . .
  

   

  

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