Three enigmatic bioh isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-tb drug target

HIGHLIGHTS

• who: Yongchang Xu et al. from the University School of Medicine, Hangzhou, Zhejiang, The People`s Republic of China, Shanghai Public have published the research work: Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target, in the Journal: (JOURNAL) of May/24,/2022
• what: The authors report that three evolutionarily-distinct BioH isoenzymes (BioH1 to BioH3) are programmed in biotin synthesis of Mycobacterium smegmatis. The authors determine the crystal structure of dimeric BioH3 at 2.27u00c5 featuring a unique lid domain. To seek how . . .
  

   

  

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