Thromboembolic events in users of warfarin treated with different skeletal muscle relaxants

HIGHLIGHTS

• who: Charles E. Leonard and collaborators from the Center for Real-World Effectiveness and Safety of Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA have published the research: Thromboembolic Events in Users of Warfarin Treated with Different Skeletal Muscle Relaxants, in the Journal: (JOURNAL)
• what: Using an epidemiologic design that inherently controls for measured and unmeasured static confounders, adjusting for critical time-varying confounders, and using a negative control, we identified a potential >3-fold increase in the rate of thromboembolism in concomitant users of warfarin + tizanidine vs. warfarin alone.
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