Thrombomodulin activation driven by lxr agonist attenuates renal injury in diabetic nephropathy

HIGHLIGHTS

  • who: Wei Wang from the Ohio State University Hospital, United States have published the paper: Thrombomodulin activation driven by LXR agonist attenuates renal injury in diabetic nephropathy, in the Journal: (JOURNAL)
  • what: The authors evaluated the serum levels of FXIII-A and TM, the expression of TM, LXR-u03b1 and FXIII-A in the renal tissue of patients with type 2 diabetic nephropathy. The authors aimed to reveal the interaction between FXIII-A and TM activation and their protective effects against renal injury in db/db mice after up-regulating/down-regulating TM expression. The . . .

     

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