HIGHLIGHTS
- who: Ann Hematol ( and collaborators from the (UNIVERSITY) have published the article: Thrombotic complications without evidence of hemolysis in paroxysmal nocturnal hemoglobinuria: is eculizumab indicated?, in the Journal: (JOURNAL)
SUMMARY
Eculizumab treatment was considered, but because of the complete absence of intravascular hemolysis, the effect of the anticoagulant therapy was awaited. Thrombosis is the most feared and life-threatening complication in PNH patients, because after onset, it is frequently progressive and refractory to anticoagulant therapy. The mechanism of thrombotic complications in PNH is not completely understood, but it has mainly been attributed to . . .
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