HIGHLIGHTS
- who: Rayene Benlaribi from the (UNIVERSITY) have published the paper: Thymic self-antigen expression for immune tolerance and surveillance, in the Journal: (JOURNAL)
- what: In the thymic medulla, depending on the binding affinity and avidity of the TCR and self-antigens, differentiating T_cells are eliminated by negative selection or converted into Tregs to ensure immune homeostasis.
- future: Research on the mechanisms of autoantigen expression and T_cell selection in the thymus is not only important for basic research but is also expected to lead to the development of new immunological diagnostic and therapeutic techniques . . .
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