HIGHLIGHTS
- who: November et al. from the University of Birmingham, United Kingdom have published the research: Thymic stromal lymphopoietin-stimulated CD4 T cells induce senescence in advanced breast cancer, in the Journal: (JOURNAL)
- what: The authors investigated the role of TSLP induction during Frontiers in Cell and Developmental Biology advanced breast cancer development using the PyMt cell line model in the context of TSLP induction in Tslptg mice (Demehri et_al, 2016; Saxena et_al, 2018). The authors show that TSLP-stimulated CD4+ T_cells are sufficient to establish this antitumor phenotype, which is associated with Th2 polarization.
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