Tiam2 contributes to osimertinib resistance, cell motility, and tumor-associated macrophage m2-like polarization in lung adenocarcinoma

HIGHLIGHTS

• who: Lu Liang et al. from the The Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, Hunan Normal University, Changsha, China have published the paper: TIAM2 Contributes to Osimertinib Resistance, Cell Motility, and Tumor-Associated Macrophage M2-like Polarization in Lung Adenocarcinoma, in the Journal: (JOURNAL) of 20/05/2022
• what: Coincidentally, several studies have shown that immune checkpoint genes CSF1R and HAVCR2 are closely associated with the induction of TAMs polarization toward the M2 phenotype , and chemokine CCL2 plays a key role in the recruitment of macrophages to neoplastic tissue . . .
  

   

  

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