Ticagrelor reduces doxorubicin-induced pyroptosis of rat cardiomyocytes by targeting gsk-3β/caspase-1

HIGHLIGHTS

• who: Shu-hui Wang from the The University of Texas MD Anderson Cancer Center, United States have published the research work: Ticagrelor reduces doxorubicin-induced pyroptosis of rat cardiomyocytes by targeting GSK-3u03b2/caspase-1, in the Journal: (JOURNAL)
• what: The work demonstrates a new pharmacological function of ticagrelor: inhibition of pyroptosis in cardiomyocytes through GSK-3u03b2.
• how: One-way analysis of variance followed by the Bonferroni post-hoc test was used to compare multiple groups. The results showed that after Dox administration the proportion of p-GSK-3u03b2 positive heart slices decreased . . .
  

   

  

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