HIGHLIGHTS
- who: Marie Platel and colleagues from the Department of Genome Biology, Institute for Integrative Biology of the Cell (I BC), CNRS, CEA, Paris South University, Gif sur Yvette, France have published the article: Tight Chk1 Levels Control Replication Cluster Activation in Xenopus, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0129090]. June 5, 2015 of /1371/
- what: By specific inhibition using UCN-01 and AZD-7762 or immunodepletion of Chk1 the authors show that Chk1 regulates the spatio-temporal replication program at the level of replication clusters and not inside active clusters-both . . .
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