Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model

HIGHLIGHTS

  • who: Maxim Moreau and collaborators from the (UNIVERSITY) have published the paper: Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model, in the Journal: (JOURNAL)
  • what: The aim of this prospective, randomized, controlled, double-blind study was to evaluate the effects of tiludronate (TLN), a bisphosphonate, on structural, biochemical and molecular changes and function in an experimental dog model of osteoarthritis (OA). The authors hypothesized that the bone anti-resorptive action of TLN might curb the development of structural and functional joint lesions associated with ACL transection. This . . .

     

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