HIGHLIGHTS
- who: Ornella Pagliano and collaborators from the DepartmentUniversity of Myers Squibb, Redwood City, California, USA have published the article: Tim-3 mediates T_cell trogocytosis to limit antitumor immunity, in the Journal: (JOURNAL)
- what: The authors show that human programmed cell death 1-positive (PD-1+) Tim-3+CD8+ tumor-infiltrating lymphocytes (TILs) upregulate phosphatidylserine (PS) a receptor for Tim-3 and acquire cell surface myeloid markers from antigen-presenting cells (APCs) through transfer of membrane fragments called trogocytosis. Mice of both sexes were used throughout the study; sex-matched and age-matched (8-12 weeks . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.