Time-resolved microfluidics unravels individual cellular fates during double-strand break repair

HIGHLIGHTS

  • who: Nadia Vertti-Quintero from the UMR3525, Paris, France have published the research: Time-resolved microfluidics unravels individual cellular fates during double-strand break repair, in the Journal: (JOURNAL)
  • what: The authors show here how to detect the DSBR dynamics at the single-cell level, by combining genetically modified cells with microfluidics and time-lapse microscopy. By following the progeny of hundreds of individual cells, the authors provide a new framework to bridge the scales between the single-cell behavior and population dynamics.
  • how: Next the model predictions for the population fractions in . . .

     

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