Timing is everything: structural insights into the disease-linked kv3 channels controlling fast action-potential firing in the brain

HIGHLIGHTS

  • who: Martin J. Gunthorpe from the (UNIVERSITY) have published the Article: Timing is everything: structural insights into the disease-linked Kv3 channels controlling fast action-potential firing in the brain, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 13/05/2022
  • what: The work of Chi et_al was focused on Kv3.1, but an understanding of the structural differences across the Kv3.1-Kv3.4 channel subtypes will surely follow and could even lead to the knowledge-based design of sub-type selective agents that could provide superior therapeutic agents in some circumstances.
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