Timp-3 facilitates binding of target metalloproteinases to the endocytic receptor lrp-1 and promotes scavenging of mmp-1

HIGHLIGHTS

• who: Anna P. Carreca from the DepartmentUniversity of have published the paper: TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1, in the Journal: Rheumatology and Musculoskeletal Sciences,

SUMMARY

The catalytic domain of human MMP-1 (MMP-1ΔC), full length MMP-1 and MMP-1 ­E200A18; recombinant His-tagged ­RAP14; FLAG-tagged ADAMTS-4 lacking the C-terminal spacer d ­ omain; FLAG-tagged ADAMTS-5 lacking the C-terminal thrombospondin domain and lacking the C-terminal thrombospondin and spacer ­domains; FLAG-tagged . . .

 



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