Tip110/sart3-mediated regulation of nf-κb activity by targeting iκbα stability through usp15

HIGHLIGHTS

  • who: Khalid Amine Timani from the Department of Microbiology and Immunology, Rosalind Franklin University, Chicago Medical School, North Chicago, IL, United States have published the research: Tip110/SART3-Mediated Regulation of NF-u03baB Activity by Targeting Iu03baBu03b1 Stability Through USP15, in the Journal: (JOURNAL) of 24/Dec/2021
  • what: The authors showed that Tip110 expression regulates TNF-a-induced NF-kB activation, and the nuclear localization signal on Tip110 is required for this activation.
  • how: The authors explored the potential mechanism underlying the Tip110-mediated NFkB activity by studying its effects on IkBa . . .

     

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