Tip47 is required for the production of infectious hiv-1 particles from primary macrophages address: 1institut

HIGHLIGHTS

  • who: Retrovirology and colleagues from the Université Pasteur, Paris, France have published the Article: TIP47 is required for the production of infectious HIV-1 pArticles from primary macrophages Address: 1Institut, in the Journal: (JOURNAL) of 23/09/2009
  • what: The authors investigated the role of the cellular cofactor TIP47 in HIV-1 morphogenesis in primary macrophages.

SUMMARY

    Macrophages are, along with T CD4+lymphocytes, the major targets of HIV-1 infection and play a key role in viral pathogenesis as a significant reservoir. Identification of the cellular cofactors involved in the . . .

     

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