Tissue-based il-10 signalling in helminth infection limits ifnγ expression and promotes the intestinal th2 response

HIGHLIGHTS

  • who: Holly C. Webster from the Mice and infection C BL/, mice were purchased from Envigo (Huntingdon, UK)B6.4get mice were kindly provided by Professor Judi Allen (University of Manchester) and bred in-house at the University of Glasgow. These mice were first developed by Mohrs et_al50. Il10gfp-foxp3rfp , mice were bred in-house (University of Glasgow). These mice express two separate transgenes: IRESeGFP inserted at the last exon and before the polyadenylation site of the Il, gene, and IRES-RFP inserted at this site of the Foxp, gene45. For each experiment mice were sex-matched . . .

     

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