Tissue catabolism and donor-specific dexamethasone response in a human osteochondral model of post-traumatic osteoarthritis

HIGHLIGHTS

  • who: Rebecca Mae Black from the Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA have published the paper: Tissue catabolism and donor-specific dexamethasone response in a human osteochondral model of post-traumatic osteoarthritis, in the Journal: (JOURNAL)
  • what: This osteochondral human ex vivo model of PTOA allowed for the analysis of disease progression and Dex effects in the context of both cartilage and bone starting with healthy tissue.
  • future: Investigation of clinical samples from many Dex-treated patients is necessary to follow up on these results.

SUMMARY . . .

 

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