Tissue losses and metabolic adaptations both contribute to the reduction in resting metabolic rate following weight loss

HIGHLIGHTS

• who: Alexandra Martin from the The present investigation is a secondary analysis of data from CALERIE [25], a randomized clinical trial in humans that involved a, % reduction in energy intake over the course of a, year periodCALERIE was chosen because it examined long-term weight loss in a free-living study and the design enabled examination of variability in the causes of RMR reductions secondary to weight loss, as well as changes in body composition and hormonal concentrations. All participants signed an informed consent before study participation. Institutional review boards at Pennington Biomedical Research Center, Washington University . . .
  

   

  

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