Tissue specific requirement of rcd4 for centriole duplication and ciliogenesis

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  • who: Pallavi Panda et al. from the of Genetics, University of Cambridge, Cambridge, UK have published the Article: Tissue specific requirement of Rcd4 for centriole duplication and ciliogenesis, in the Journal: (JOURNAL) of 01/09/2022
  • what: The authors show that rcd4 mutants exhibit fewer centrioles, aberrant mitoses, and reduced basal bodies in sensory organs. The authors show that Rcd4 and Ana3 directly interact to form a heterodimeric complex and that the timing of its recruitment to the centriole suggests a role in centriole to centrosome conversion. Secondary antibodies conjugated with Alexa Fluor 488, 568 . . .

     

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