HIGHLIGHTS
- who: Mathilde Biola-Clier and collaborators from the Laboratoire Innovations technologiques pour la Détection et le Diagnostic (Li D), Service de Pharmacologie have published the research: Titanium Dioxide NanopArticles Alter the Cellular Phosphoproteome in A549 Cells, in the Journal: (JOURNAL)
- what: These molecular mechanisms TiO2 -NP toxicity have been reported previously the study shows for the first time that they may derive from phosphoproteome modulation which could be one their upstream regulators. Protein phosphorylation/dephosphorylation reactions, carried out by kinases and phosphatases, regulate the activity of almost all cellular processes TiO2 shows high affinity . . .
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