Title :

HIGHLIGHTS

• who: Xie and collaborators from the University of California, Davis, Sacramento, CA, USA have published the article: Title :, in the Journal: (JOURNAL)
• what: The authors demonstrate that acral skin has low expression of EOS acyl-ceramides and the genes involved in their synthesis as well as low expression of genes involved in filaggrin and keratin citrullination (PADI1 and PADI3) and corneodesmosome degradation changes consistent with increased corneocyte retention. In the current report, the authors demonstrate that KRT1 is strongly upregulated in acral keratinocytes. In contrast to these prior studies, the authors demonstrate that ceramide sphingoid . . .
  

   

  

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