Tlr agonists induce sustained igg to hemagglutinin stem and modulate t cells following newborn vaccination

HIGHLIGHTS

  • who: Elene A. Clemens from the Animals Newborn AGM used in this study were housed at the Wake Forest University School of Medicine African green monkey Research ColonyNewborns were mother-reared and housed in social groups throughout npj Vaccines (2022) , have published the research: TLR agonists induce sustained IgG to hemagglutinin stem and modulate T cells following newborn vaccination, in the Journal: (JOURNAL)
  • what: This study shows that inclusion of TLR7/8 adjuvant R848 in an inactivated IAV vaccine can promote a lasting IgG response to the HA stem, while the TLR5 agonist flagellin produces . . .

     

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