Tlr7 and igm: dangerous partners in autoimmunity

HIGHLIGHTS

  • who: Timm Amendt and Philipp Yu from the Institute of Immunology, University Hospital Ulm, Ulm University, Ulm, Germany have published the Article: TLR7 and IgM: Dangerous Partners in Autoimmunity, in the Journal: Antibodies 2023, 12, 4. of /2023/
  • what: And Outlook

SUMMARY

    In contrast, patients that are incapable of classswitching to IgG, thus only able to produce IgM antibodies (hyper‐IgM‐syndrome switching to IgG, thus only able to produce IgM antibodies (hyper-IgM-syndrome ) ) often show severe autoimmunity. Wasthe shown that the type ofpresent glycans is important the effectorfor function . . .

     

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