HIGHLIGHTS
- who: Grant J. Brown from the Centre for Personalised Immunology, Department of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory, Australia Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia. China Australia Centre for Personalised , have published the paper: TLR7 gain-of-function genetic variation causes human lupus, in the Journal: (JOURNAL) of 20/01/2021
- what: The authors show that enhanced TLR7 signalling drives aberrant survival of B cell receptor (BCR)-activated B cells, and in a cell-intrinsic manner, accumulation of . . .
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