Tnfα induces survival through the flip-l-dependent activation of the mapk/erk pathway

HIGHLIGHTS

  • who: F Marques-Fernandez from the Institut Spain and Laboratoris Clinics, Hospital Universitari Vall d`Hebron, Passeig Vall d`Hebron, Barcelona, Spain have published the Article: TNFu03b1 induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway, in the Journal: (JOURNAL)
  • what: The authors show here that TNFa treatment induces apoptosis when either NF-kB or MAPK/ERK pathway is blocked. As the authors demonstrate here that FLIP-L is necessary for TNFa-induced MAPK activation, the authors further analyzed the upstream step that is critical for this event. The authors . . .

     

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