Tnf-α promotes lpa1- and lpa3-mediated recruitment of leukocytes in vivo through cxcr2 ligand chemokines[s]

HIGHLIGHTS

  • who: Chenqi Zhao from the Laval University have published the research: TNF-α promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines[S], in the Journal: (JOURNAL) of 27/04/2010
  • what: The authors demonstrate that both LPA1 and LPA3 mediate the recruitment of leukocytes into the air pouch through a mechanism that is dependent on LPA-mediated chemokine synthesis and exacerbated by the pro-inflammatory cytokine TNF-␣. Data represent the mean ± SE of three to five mice per group. *P and amp;lt; 0.05; **P and amp;lt; 0 . . .

     

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