Tnf a -induced apoptosis enabled by ccn1/cyr61: pathways of reactive oxygen species generation and cytochrome c release

HIGHLIGHTS

  • who: Cytochrome c Release and colleagues from the Department of Biochemistry and Molecular Genetics, University of Illinois College of Medicine, Chicago, Illinois, United States of America have published the research: TNF a -Induced Apoptosis Enabled by CCN1/CYR61: Pathways of Reactive Oxygen Species Generation and Cytochrome c Release, in the Journal: (JOURNAL) of February/17,/2012
  • what: The authors show for the first time that CCN1 interacts with the low density lipoprotein receptor-related protein 1 (LRP1) in a protein complex and that binding to LRP1 is critical for CCN1-induced ROS generation and apoptotic . . .

     

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